gene mutation
noun
plural gene mutations
: a permanent alteration (as by point mutation or frameshift mutation) in the nucleotide sequence of a gene
Researchers have identified a gene mutation that's believed to predispose people to malignant melanoma, the deadliest and most aggressive type of skin cancer.—
Health News
compare point mutation
Health NewsExamples of gene mutation in a Sentence
Recent Examples on the Web
Years prior, the couple had her husband tested for the CFTR gene mutation, just in case.
—Jordan Greene, People.com, 24 June 2025
Durand predicts that in the next decade, medical practice may move towards offering full-body imaging to more groups that are at high risk for cancer, like those with BRCA gene mutations or Lynch syndrome.
—Claire Bugos, Verywell Health, 18 June 2025
The gene mutations linked to sporadic hemiplegic mutation occur spontaneously in the person with the disorder.
—Colleen Doherty, Verywell Health, 26 May 2025
Does that mean the gene mutation in each of his liver cells is now fixed?
—German Lopez, New York Times, 16 May 2025
See All Example Sentences for gene mutation
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Jordan Greene, People.com, 24 June 2025
Durand predicts that in the next decade, medical practice may move towards offering full-body imaging to more groups that are at high risk for cancer, like those with BRCA gene mutations or Lynch syndrome.
—Claire Bugos, Verywell Health, 18 June 2025
The gene mutations linked to sporadic hemiplegic mutation occur spontaneously in the person with the disorder.
—Colleen Doherty, Verywell Health, 26 May 2025
Does that mean the gene mutation in each of his liver cells is now fixed?
—German Lopez, New York Times, 16 May 2025
See All Example Sentences for gene mutation
Cite this Entry
“Gene mutation.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/gene%20mutation. Accessed 21 Jul. 2025.
Copy CitationMedical Definition
gene mutation
noun
: a permanent alteration (as a point mutation or frameshift mutation) in the nucleotide sequence of a gene
… there is a 50 percent chance each offspring will inherit the gene mutation and may develop the disease.—Fred Cicetti
Fred CicettiIn early August the team published a study in Nature that chronicled how a single gene mutation in a laboratory strain of Escherichia coli could create a bacterium resistant to triclosan …—Gary Stix
Gary StixLove words? Need even more definitions?
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